Lecture 1: About the course (Readings: None, 281_Lec1)
Lecture 2: General introduction (Readings: Chapter 1, 281_Lec2)
Lecture 3: The identity and location of the genetic material (Readings: Chapter 2, 281_Lec3, Puzzle3)
Lecture 4: DNA: chemical composition (Readings: Chapter 2, 281_Lec4, Puzzle4)
Video: DNA building blocks
Lecture 5: DNA: the double helix structure (Readings: Chapter 2, 281_Lec5, Puzzle5)
Video: The DNA double helix discovery
Video: Pauling triplet helix
Video: James Watson – Basepairing
Video: Chargaff’s rule
Video: The double strands
Lecture 6: DNA: genome organization (Readings: Chapter 2, 11, 281_Lec6)
Video: DNA packaging – Basic
Video: DNA packaging – Advanced
Lecture 7: DNA: replication experiments (Readings: Chapter 10, 281_Lec7)
Video: DNA structure and replication
Lecture 8: Prokaryotic replication: elements (Readings: Chapter 10, 281_Lec8, Puzzle6)
Lecture 9: Prokaryotic replication: process (Readings: Chapter 10, 281_Lec9, Puzzle7)
Lecture 10: Eukaryotic and phage replication (Readings: Chapter 10, 281_Lec10, Puzzle8)
Video: DNA replication – Basic
Video: DNA replication – Advanced
Lecture 11: Transcription (Readings: Chapters 4, 5, & 6, 281_Lec11 , Puzzle9)
Lecture 12: Transcription in prokaryotes (Readings: Chapters 4, 5, & 6, 281_Lec12 , Puzzle10)
Lecture 13: Transcription in eukaryotes (Readings: Chapters 4, 5, & 6, 281_Lec13 , Puzzle11)
Video: Transcription – Basic
Video: Transcription – Advanced
Video: Eukaryotic mRNA splicing
Lecture 14: The genetic code (Readings: Chapter 7, 281_Lec14 , Puzzle12)
Video: The Triplet Code
Lecture 15: Amino acids and proteins (Readings: Chapters 7 & 8, 281_Lec15 , Puzzle13)
Lecture 16: Translation: tRNA and rRNA (Readings: Chapters 5, 6, 7, & 8, 281_Lec16)
Lecture 17: Translation in prokaryotes (Readings: Chapters 7 & 8, 281_Lec17)
Lecture 18: Translation in eukaryotes (Readings: Chapters 7 & 8, 281_Lec18)
Video: Translation – Basic
Video: Translation – Advanced
Lecture 19: Regulation of gene expression: Generalities (Readings: Chapter 9, 281_Lec19)
Lecture 20: Lambda phage repressor (Readings: Chapter 9, 281_Lec20)
Lecture 21: Prokaryotic regulation (Readings: Chapter 9, 281_Lec21)
Lecture 22: Eukaryotic regulation (I) (Readings: Chapter 9, 281_Lec22)
Lecture 23: Eukaryotic regulation (II) (Readings: Chapter 9, 281_Lec23)
Lecture 24: Eukaryotic regulation (III) (Readings: Chapter 9, 281_Lec24)
Lecture 25: DNA mutation (Readings: Chapter 16, 281_Lec25)
Video: The Fly Room
Movie: Mutation – The science of survival
Lecture 26: Point mutations (Readings: Chapter 16, 281_Lec26)
Lecture 27: Chromosomal mutations (Readings: Chapter 16, 281_Lec27)
Lecture 28: Sources of mutations (Readings: Chapter 16, 281_Lec28)
Lecture 29: DNA repair (Readings: Chapter 16, 281_Lec29)
Extra material not needed for exams but interesting to know!
Extra lecture 1: ModelOrganisms, Puzzle1.
Fun reads: What are model organisms?
Extra lecture 2: MendelANDGenetics, Puzzle2.
Extra lecture 3: DNA_Extraction
Video: How to extract DNA from strawberries
Extra lecture 4: DNA_Quality_Quantity
Extra lecture 5: PCR_DNAsequencing
Video: Polymerase Chain Reaction
Video: Sanger Sequencing
Video: PCR song
Video: Bio Rad GTCA song
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