Category Archives: Intro. Mol. Genetics (371)

Material and announcements for the Introduction to Molecular Genetics will be posted here

Introduction to Molecular Genetics (371)

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Class time and location
Mon, Wed – 11:00-12:15 (Room: 1st floor, SCI-S Room 199)
Textbook, readings, and lecturing style:
Molecular Biology of the Gene. 6th edition, by Watson et al.
The lectures will be given using powerpoint slides (see below). It is YOUR RESPONSIBILITY to print the material, come to the lectures, and take notes. You will be tested on the material I give in class and the book.
Attendance:
I will not give points for attending my lectures. You are a RESPONSIBLE student and you want to learn. Missing lectures will significantly affect your performance and grade. I do not intend to give lectures during my office hours or photocopy my lecture notes for you!
Academic dishonesty:
DO NOT CHEAT. You are smart and you can get the grade you want. Academic dishonesty will not be tolerated.
Tests and grading:
You will be given FOUR independent tests each of which covers specific chapters. Each test is worth 30%. Your lowest test grade will be dropped and your final grade will be the sum of the three highest scores in addition to the final. The final is worth 40% and will cover the entire course material with greater emphasis on the material that you have not been tested on. The tests will be a combination of multiple-choice questions and short answer ones. 
Important dates:
Exam1: Monday 11/3/2024 (Lectures 1-11), Bonus1 due
Exam2: Monday 8/4/2024 (Lectures 12-20), Bonus2 due
Exam3: Wednesday 8/5/2024 (Lectures 21-), Bonus3 due
Final Exam: Saturday 18/5/2024 – 11:00-1:00, Bonus4-5 due
Enrolled students:
  1. Afrah Alshammari./
  2. Fatima Abbad./
  3. Manar Saeed./
  4. Farah Alenezy./
  5. Maali Almutairi./
  6. Jumanah Alhendal./
  7. Maha Al-Bulushi./
  8. Samiyah Janadeleh./
  9. Malak Mahmood./
  10. Alritaj Alkhaldi./
  11. Al-Waleed Salmaan./
  12. Shaimaa Alajmi./
  13. Farah Alhbiarh./
  14. Abeer Alshammari./
  15. Sharifah Alwhaib./
  16. Asmaa Alshaijy./
  17. Asmaa Alsaeed./
  18. Shahad Alenezi./
  19. Salma Alantari./
  20. Althuraya Alaskar./
  21. Rufaida Negm./
Lecture 1: General Introduction (371_Lec1)
Lecture 2: Model organisms (371_Lec2)
Lecture 3: Laws of inheritance (371_Lec3)
Lecture 4: Mendel’s monohybrid experiments (371_Lec4)
Video: How Mendel’s pea plants helped us understand genetics? – Thanks Fatemah Sadeq
Lecture 5: Mendel’s dihybrid experiments (371_Lec5)
Lecture 6: The location and identity of the genetic material (371_Lec6)
Lecture 7: The identity of the genetic material (371_Lec7)
Lecture 8: The chemical composition of the genetic material (371_Lec8)
Video: DNA building blocks
Video: The structure of DNA – Thanks to Asmaa Alghanem
Lecture 9: DNA: The double helix structure (371_Lec9)
Video: The DNA double helix discovery
Video: Pauling triplet helix
Video: James Watson – Basepairing
Video: Chargaff’s rule
Video: The double strands
Lecture 10: Genome organization (371_Lec10)
Video: DNA packaging – Basic
Lecture 11: Genome organization: eukaryotes (371_Lec11)
Video: DNA packaging – Advanced
Lecture 12: DNA: Replication experiments (371_Lec12)
Video: DNA structure and replication
Lecture 13: DNA replication in prokaryotes: The elements of replication (371_Lec13)
Lecture 14: DNA replication in prokaryotes: The process of replication (371_Lec14)
Video: DNA replication – Thanks to Asmaa Alghanem
Video: DNA replication – Basic
Video: DNA replication – Advanced
Lecture 15: DNA replication in eukaryotes and phage (371_Lec15)
Video: Telomere replication – Thanks Nutaila Almahfudhi
Lecture 16: Transcription (371_Lec16)
Fun reads: 60 years ago, Francis Crick changed the logic of biology, Matthew Cobb
Lecture 17: Transcription in prokaryotes (371_Lec17)
Video: Transcription – Basic
Video: Transcription – Advanced
Lecture 18: Transcription in eukaryotes (371_Lec18)
Video: Eukaryotic mRNA splicing
Video: Eukaryotic mRNA Transcription – Thanks Rufaida Negm
Lecture 19: The genetic code (371_Lec19)
Video: The Triplet Code
Video: Ribosome binding assay – Thanks Haya Alshammari
Lecture 20: Amino acids and proteins (371_Lec20)
Video: Protein Structure and Folding – Thanks Althuraya Alaskar
Lecture 21: Translation: The tRNA and rRNA (371_Lec21)
Lecture 22: Translation in prokaryotes (371_Lec22)
Video: Translation – Basic
Video: Translation – Advanced
Lecture 23: Translation in eukaryotes (371_Lec23)
Video: Eukaryotic Translation – Thanks Fatima Baabbad
Lecture 24: Regulation of gene expression: I. Generalities (371_Lec24)
Lecture 25: Regulation of gene expression: II. Lambda (λ) phage repressor (371_Lec25)
Lecture 26: Regulation of gene expression: III. Prokaryotic regulation (371_Lec26)
Video: Lac Operon – Thanks Battol Samaro
Lecture 27: Regulation of gene expression: IV. Eukaryotes (part 1) (371_Lec27)
Lecture 28: Regulation of gene expression: IV. Eukaryotes (part 2) (371_Lec28)
Lecture 29: Regulation of gene expression: IV. Eukaryotes (part 3) (371_Lec29)
Lecture 30: Mutations (371_Lec30)
Lecture 31: Point mutations (371_Lec31)
Lecture 32: Chromosomal mutations (371_Lec32)
 Lecture 33: Sources of mutations ()
Lecture 34: DNA repair ()
Figures, photos, and graphs in my lectures are collected using google searches.  I do not claim to have personally produced the material (except for some). I do cite only articles or books used. I thank all owners of the visual aid that I use and apologize for not citing each individual item.  If anybody finds the inclusion of their material in my lectures a violation of their copy rights, please contact me via email (hhalhaddad@gmail.com).