Shouq Alazmi (485)

Bashayer Jamal (485)

Shaikha Alshariafi (485)

Anfal Alsahaf (281)

Badreya Alnassar (281)

Very nice poem by Zainab Ahmed from my Genomics class.

Nice one by my 485 student: Hanan M. Ali

This is a very nice creative work one of my former students, Fahad Alenizi.  Fahad is a very talented Arabic calligrapher especially in Dewani style.  This work was a collaboration between Fahad and my graduate student Huda Alaskar, a promising English calligrapher and the person who digitized the work.

The following are some nice artistic 899km from my student Fatima Jawad from Oman.  Very Nice!!!!

This is an interesting creative work by my student in the Intro. to Mol. Biol. (281) Summer course Abrar Alsharaf.  Very nice.

• الكثرة تغلب الشجاعة وكثرة ال (Methylation) في ال (CpG islands) تغلب شجاعة ال (RNA pol)

شريفة إبراهيم

• DNA said to mRNA at a checkpoint:

أكاد أشك في نفسي لأني أكاد أشك فيك وأنت مني

سارة سعيد

هو الكون حي يحب الحياة

ويحتقر ال (mutation) مهما كبر

فلا الأفق يحضن غريب الطيور

ولا النحل يلثم عجيب الزهر

ولولا أمومة قلبي الرؤوم

لما ظل لل (mutation) مستقر

آمنه عبدالله

نقولهم تيس ويقولون إحلبوه. ونقولهم (DNA strand) يقولون سوو له (Translation)

فاطمة سليم

ال (RNA interferance) مطبق مقولة: الحشرة مع ال (molecules) عيد

سارة فهد

خط ال (Repressors and activators) بال (Nucleus) واقعد بالظلال

دلال خليفة

The difference between the ordinary and the extraordinary is just the little “Extra”. This is just like the “Extra” chromosome in Down syndrome

Sara Zeyad

•  هذا الشبل من ذاك الأسد. وهذا ال (chromatin) من ذاك (chromosome)
• الشريجة تحر ولو بالقبر وال (repressor) يحر ال (activator) ولو بال (DNA)
• كثر الدق يفك اللحام وكثر ال (abortive initiation) يفك ال (RNA pol) عن ال (promoter)

مشاعل الكندري

ربع(ن) تعاونوا ما ذلوا. مثل ال (helicase) و ال (helicase loader) يتعاونون على ال (DNA double strands)

ريوف فايز

Here is another thoughtful story by my active, enthusiastic, and outstanding student, Zahraa Hasan.

When I studied alternative splicing in 281 course, the instructor [Hasan] said that the possible combinations are unlimited [exaggeration by Hasan]. I wanted to see if it is truly unlimited or it is possible to calculate it.

I thought that I can calculate it by using permutations and combinations but those approaches did not work. The Permutations did not work because it allows the second exon to become before the first exon, and this is not possible in genes. Combinations did not work because it does not deal with the order. So, I realized that I had to find the formula that can be used for this process by trying every possible combination for the exons. At the end I found it : 2^{(#of exons – 2)}. The (-2) is in the formula because the first exon contains the AUG codon (the beginning of the gene), and the last exon contains a stop codon, so a protein cannot theatrically be synthesized if either the first exon or the last exon is not included.

Given:

1. The human gene with the largest number of exons is (TTN gene)
2. TTN gene has 363 exons.
3. TTN gene cDNA size is 82Kb.
4. TTN codes for Titin protein.
5. TTN protein contains 26,926 amino acids and a mass of 2993kDa.

The theoretical possible combinations of TTN exons would be

2^(363-2) = 4.69×10¹⁰⁸ possible combinations !!!

This formula can be used only for skipping exons in the alternative splicing process.